
Fast-acting within 20 minutes. Sustained Release (SR) for 8 hours. Ingredients backed by 198+ clinical studies.
Custom formulated by Sunil Pai MD, leading expert in Integrative Medicine and best-selling author of An Inflammation Nation: The Definitive 10-Step Guide to Preventing and Treating All Diseases through Diet, Lifestyle, and the Use of Natural Anti-Inflammatories.
Fast-Acting
Long-Lasting
100% Natural
Clinically Proven
Free shipping with 3-pack bundle or more
9,000+ patients at Sanjevani successfully treated
Over 100,000+ satisfied customers worldwide
The "gold standard" industry leading formula since 2010


(verified reviews)
PER BOTTLE

Inflammation is the triggering mechanism of almost all diseases.
THE SUFFIX "-ITIS" = INFLAMMATION
There are over 200 -"itis" conditions.
EXAMPLES OF INFLAMMATORY CONDITIONS:
Arthritis (joint pains), Conjunctivitis (red eyes), Rhinitis (runny nose), Dermatitis (eczema), Sinusitis (sinus infections), Gingivitis (swollen gums), Thyroiditis (autoimmune), Bronchitis (lung inflammation), Esophagitis (GERD), Gastritis (stomach pain), Colitis, Prostatitis, Vaginitis, and more...
Chronic inflammation leads to chronic diseases.
You might be experiencing one or many of these conditions now and over your lifetime, but were never given a safe option to reduce your symptoms and heal your body.

This is where Bosmeric-SR® is the solution.
It is not only a safe and effective NSAID alternative but it's so much more.
Research shows that the precise combination of Curcumin C3 Complex®, Boswellin PS®, Ginger, and Bioperine® at specific potencies lowers not just one pathway but over 97+ different pathways and mechanisms of inflammation.1†
There is No Black Box Warning.
No unwanted effects. Just safe and effective results.
Better yet, the patented ingredients in Bosmeric-SR® acts on mono-targets (direct pathways) and multi-targets (categories of mechanisms) that are involved with inflammation. They also have been shown to up-regulate and down-regulate gene expressions - all related to healing and longevity.2†



Curcumin and Boswellia: Important pathways and mechanisms of action.2,3


Ginger and Black Pepper: Important pathways and mechanisms of action.4,5

3 patented ingredients, one with highest potency available.
The patented compounds at exact doses used in the clinical studies.
Clinically tested and used in hospitals and top research centers worldwide.
Grown with Sustainable Cultivation Programs with Good Agricultural Practices (GAP).6
USP, NSF GMP and American Botanical Council certifications.7
No generic extracts, no fillers.
No synthetics. No nano particles. Non-GMO. Non-Irradiated. No solvents.
No Pesticides. No Heavy Metals.

Bi-Layered Caplet delivery system separates ingredients to prevent degradation, ensuring 100% potency at the moment of consumption.
It also provides a fast acting benefit within 20 minutes and Sustained Release (SR) over 8 hours.
A formulation not available in any other supplement.

Direct ingredient benefits verified by 198+ clinical studies, 185+ pre-clinical studies and 64 review articles.8,9,10,11,12,13,14,15
GRAS affirmed by FDA and safety studies.8
Trusted by physicians and researchers for over 20+ years. The preferred branded ingredients used at NIH (National Institutes of Health) and top universities such as University of Texas -MD Anderson Cancer Center, Tufts, Rutgers and University of California.9
Used safely and effectively by tens of thousands of people worldwide.9


100% potency maintained until the moment you swallow the caplet.

Water soluble ingredients immediately absorb into the bloodstream.

Therapeutic levels reached across multiple inflammation pathways.

Bi-layer delivery system slowly releases for all-day relief.
Ingredients such as ginger, bromelain, papain, nattokinase, proteolytic enzymes in capsules or tablets begin to degrade all the other ingredients while they remain in the bottle, resulting in up to 60% potency loss before you even take them.16,17.18,19
Unique Bi-layered caplet manufacturing separates the ingredients into individual layers and sections which ensures 100% potency is maintained at the moment you take it — guaranteed. Furthermore, it allows for a fast action within 20 minutes and sustained release over 8 hours (SR).

The "gold standard" curcumin brand being the most extensively studied and clinically documented.8 With over 185+ peer-reviewed studies. Utilizing the patented therapeutic ratio of the 3 most important curcuminoids:9
75-81% Curcumin
15-19% Desmethoxycurcumin
2.4-6.5% Bisdemethoxycurcumin
Bosmeric-SR® provides the sames doses of those used in clinical studies of Curcumin C3 Complex®. Additionally, it contains the amount of all the other turmeric extract compounds needed to provide Full-Spectrum benefits8 delivered in an 8-hour Bi-Layered Sustained Release (SR) caplet.
GRAS affirmed. Non-Irradiated. Non-GMO. Certified to have: No Synthetics (14C tested), No Nano-Particles, No Heavy Metals, No Pesticides, No Solvents.20
Caution: Don't assume the research applies to your curcumin product. A label stating "95% curcuminoids" does not make a product equivalent to patented Curcumin C3 Complex. Unless it contains the same specific curcuminoid ratios (above), the hundreds of studies and research on Curcumin C3 Complex can NOT be applied to prove the safety, efficacy, or benefits of any other product.

Exclusive to Bosmeric-SR®. Contains Boswellin PS® - the Polysal™ polysaccharide fraction (PS), that works synergistically with Boswellic acids and AKBBA which studies show to be the most beneficial.21, 22 Utilizing the patented therapeutic ratios of boswellia:21
35%Polysal™ (PS)
35% Boswellic acids
10% AKBBA
Bosmeric-SR® contains Boswellin PS® which is more effective than any other grade of Boswellin® and Boswellia extracts available.22,23 The unique benefits of Boswellin PS makes it water-soluble which delivers an immediate onset of action within 20 minutes. No other boswellia product on the market does this. Therefore Bosmeric-SR® provides a "fast-acting" experience which is needed for those who need quicker inflammatory support.
GRAS affirmed. Non-Irradiated. Non-GMO. Certified to have: No Synthetics. No Heavy Metals. No Pesticides.20
Caution: If you are taking a Boswellia extract that doesn't show the specific ratios of the 3 important compounds (above), then you are NOT receiving the most effective Boswellia available. Boswellin PS® has been shown to be more effective than any boswellia extract and Boswellin® compound.21.22,23

Gingerols are the important component of ginger providing the maximum benefits..24 Most premium supplements that are standardized contain only between 2-10% Gingerols.
Bosmeric-SR® provides Ginger Extract Standardized to the highest amount available worldwide:
20% Gingerols
Bosmeric-SR® protects all of its ingredients from degradation from our highest potency ginger extract and maintains 100% potency at the time you take it via our unique Bi-Layered technology.
Gras Affirmed. Non-Irradiated. Non-GMO. Certified to have: No Heavy Metals. No Pesticides.20
Caution: If your label lists only “ginger extract” without specifying the gingerol content, you will only be getting ordinary ginger powder—with significantly less potency and efficacy.
Also important: Products containing ginger, bromelain, papain, nattokinase, or proteolytic enzymes that lack a Bi-Layered delivery system may degrade all the other ingredients during storage, reducing potency and benefits over time.16,17,18

BioPerine® known as the "bioavailable enhancer."25 It increases the absorption of Curcumin C3 Complex® by 2,000%26 and Boswellin® and ginger increase up to 60%.27 In contrast to generic black pepper powder which contains only 5-9% piperine, BioPerine® is patented and standardized to:
95% Piperine
Unlike competing products that rely on microdosing, Bosmeric-SR® utilizes clinically proven dosages28 engineered to maximize curcumin absorption and deliver comprehensive health benefits.
GRAS affirmed. Non-Irradiated. Non-GMO. Certified to have: No Heavy Metals. No Pesticides.20
Caution: The improved absorption claims of 2,000% can only be used with Curcumin C3 Complex® and Bioperine® together since that is what the study shows and it does NOT apply to other generic curcumin/turmeric extracts, nor generic black pepper extracts as they have not been studied or shown to do so.

NOTE: This is not including generic studies on these ingredients. These are studies DIRECTLY using Curcumin C3 Complex, Boswellin, Ginger Extract (20% Gingerols) and BioPerine - making them the most extensively researched and clinically studied patented forms of these ingredients as of August 2026.8-15


No synthetic curcumin · No turmeric oils · No nano-particles · No pesticides · No heavy metals · No solvents ·
No choline · No soy · Non-GMO · Non-Irradiated
SINGLE-PATHWAY CASCADE
Think of it like deploying a massive fire truck hose inside a building. When aimed directly at the flames, it puts the fire out. However, that intense, localized pressure frequently misses the exact mark, leading to widespread water damage.
In medical terms, this "water damage" manifests as joint degeneration, severe gastrointestinal distress including GI bleeding and ulcers and cardiovascular side effects including heart attacks and strokes that trigger
FDA Black Box Warnings.
MULTI-PATHWAY SYNERGY
Instead of blasting the body with a single synthetic chemical, this combination acts like a sophisticated building fire sprinkler system. When a fire breaks out, the system activates calibrated, localized support across 97+ distinct pathways and mechanisms of inflammation simultaneously.1
It systematically extinguishes the issue at its root without causing collateral damage or side effects. No Black Box Warning. Some of those pathways and mechanisms also provide health benefits with regards to bolstering wellness, the immune system, and longevity.2
POLYPHARMACOLOGY & AYURVEDA
While Ayurvedic medicine has relied on these synergistic compounds for millennia, Bosmeric-SR® elevates this traditional wisdom through precision, patented ingredients and specialized manufacturing.
Utilizing an advanced Bi-Layered delivery system, it provides both immediate and sustained-release mechanisms. This ensures active ingredients deliver optimal potency immediately and maintains steady blood-plasma levels throughout the day, providing reliable, scientifically validated relief.
No other natural dietary supplement on the market can match this level of clinical precision, rapid absorption, and sustained release that provide all day benefits. Experience the premier standard of evidence-based wellness.

It is scientifically formulated using ingredients that have been carefully chosen not only for their individual therapeutic actions but also for their synergistic benefits;

All ingredients are grown through Sustainable Contract Cultivation Programs using Good Agricultural Practices (GAP) without the use of pesticides, herbicides, and are non-irradiated from selected farms. They are also manufactured in a state-of-the-art NSF GMP certified facility. Furthermore, the ingredients are 14C tested to be synthetic-free, nano-particle free, solvent-free, heavy metal-free as well as soy-free, gluten-free, choline-free, vegan, and non-GMO;

All ingredients used are the most researched, clinically tested, patented and recognized as the “gold standard” for setting the safety, efficacy, potency and purity of these active natural compounds;

Ingredients are combined using a specialized Bi-Layered delivery system ensuring 100% potency of all ingredients at the time of consumption, in addition to providing a fast acting (within 20 minutes) and Sustained Release (SR) action up to 8 hours.
Bosmeric-SR® stands alone by combining synergistic, clinically validated doses of patented natural ingredients with a specialized Bi-Layered delivery system that ensures both rapid-onset and prolonged therapeutic benefits.
Not all supplements are created equal. Here's how Bosmeric-SR® compares
to what you'll find online and store shelves.


Sunil Pai, MD is an internationally recognized expert in Integrative Medicine. One of the first physicians and youngest in the U.S. to become a Fellow of the Program in Integrative Medicine at University of Arizona (Class 2002) directed by Dr. Andrew Weil. Additionally, he has over 15 certifications in specialized trainings bringing his extensive knowledge and experience in holistic medicine to his precision in custom formulation of evidence-based natural therapies.
Dr. Pai has used Bosmeric-SR ® with his patients in over 9,000+ patients at his clinic, Sanjevani Integrative Medicine Health & Lifestyle Center and with tens of thousands of customers worldwide.
MD
Board Certified
Integrative Medicine
Neuro-Acupuncture
Functional Medicine
Ayurvedic Medicine
Plant-Based Nutrition
VERIFIED BUYERS
9,000+ SANJEVANI PATIENTS
16+ YEARS OF USE WORLDWIDE







Bosmeric-SR is formulated to support a healthy inflammatory and immune response, joint comfort, mobility, and overall wellness. Designed for daily use as part of a healthy lifestyle, it provides a natural, multi-ingredient approach to managing everyday inflammation and discomfort. For those looking to reduce their reliance on NSAIDs, Bosmeric-SR may be considered as a natural alternative to discuss with their healthcare professional.
Bosmeric-SR stands apart by replacing unstandardized ingredients with a synergistic powerhouse of four premier, clinically tested botanical extracts. While generic supplements often rely on standalone turmeric with poor absorption and sparse human data, Bosmeric-SR pairs ultra-pure active compounds with a sophisticated pharmaceutical-grade delivery system to guarantee unmatched efficacy, safety, and rapid bioavailability.
The Gold Standard of Patented Ingredients: The formulation relies exclusively on world-renowned, clinically vetted botanical complexes:
C3 Complex®: The most widely researched and trusted turmeric extract available, standardized to 95% active curcuminoids.
Boswellin® PS: A next-generation Frankincense extract containing a unique Polysal fraction along with active boswellic acids and AKBBA.
Ginger Extract (20% Gingerols): A hyper-concentrated extract delivering the highest available percentage of active gingerols for maximized digestive and systemic synergy.
BioPerine®: A patented black pepper extract standardized to 95% piperine, clinically proven to enhance the absorption and metabolic uptake of the core ingredients.
Advanced Bi-Layered Delivery System: Instead of capsules with similar ingredients that slowly dissolve each other when placed together and are shorter acting, Bosmeric-SR uses advanced bi-layer technology for a dual-action therapeutic release:
Fast-Acting Relief: An immediate-release layer activates within 20 minutes of ingestion.
Long-Lasting Coverage: A sustained-release matrix continuously delivers a steady concentration of active ingredients for up to 8 hours, maintaining a consistent therapeutic range in the bloodstream.
Uncompromising Purity & Safety: Manufactured entirely in the USA under rigorous USP and NSF GMP-certified standards, every batch is guaranteed C14 natural. The formulation contains absolutely zero synthetics, solvents, heavy metals, pesticides, GMOs, or nano-particles ensuring supreme structural stability and safety with every dose.
Bosmeric-SR delivers an immediate onset within 20 minutes of ingestion, followed by a sustained-release (SR) phase that extends up to 8 hours. Its advanced bi-layered delivery system ensures dual-action pharmacokinetic support by pairing rapid bio-availability with prolonged metabolic absorption.
Immediate Relief: Activates within 20 minutes for fast-acting, on-demand pain and inflammation support.
Extended Coverage: Continuously releases active therapeutic ingredients for up to 8 hours.
Flexible Dosing: Works as-needed for acute comfort or daily to secure compounding long-term health benefits.
The current suggested use is 2 caplets twice daily with food, or as directed by a healthcare provider. People with need of extra pain, inflammation and immune support can take 2 caplets three times a day with food for 24 hours of synergistic benefits.
Although Bosmeric-SR has been used safely in tens of thousands of patients and customers worldwide, customers taking prescription medications, managing a medical condition, or who are pregnant or nursing should check with their healthcare professional before using Bosmeric-SR.
Bosmeric-SR has been used by tens of thousands of people since 2010 with a strong history of tolerability. As with any natural product, individual sensitivities can occur, particularly to ingredients such as turmeric, ginger, or black pepper. If you have known food allergies or sensitivities, consult your healthcare provider before use.
Because of the Bi-Layered Delivery System and concentrated 20% gingerols, some people may notice a slightly pungent ginger taste when swallowing. If this occurs, simply place the yellow side of the caplet on your tongue before swallowing.
A key distinction is the purity, potency, safety and efficacy. Bosmeric-SR uses a precise combination of patented, highest clinically tested standardized ingredients, specific ingredient ratios, and its unique bi-layered delivery system with a 20 minute onset of action and 8 hour sustained-release (SR) delivery system. All these factors provide superior benefits and is why Bosmeric-SR is the "gold standard" in this category of dietary supplement. In addition, Bosmeric-SR is GRAS affirmed, Non-Irradiated, Non-GMO, gluten-free, soy-free, choline-free and plant based. Certified to have: No Synthetics, No Nano-Particles, No Heavy-Metals, No Pesticides, No Solvents and proudly manufactured in the USA.


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†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
1. Bao ZC, Liu ZD, Zhang Y, Dai HJ, Jia H, Ren F, Li N, Zhao L, Wang YW, Lv SY, Zhang Y. To investigate the effect and mechanism of tetrahydrocurcumin on hepatocellular carcinoma based on phosphoinositide 3-kinases/AKT signaling pathway. World J Gastrointest Oncol. 2025 Mar 15;17(3):102187. doi: 10.4251/wjgo.v17.i3.102187. PMID: 40092949; PMCID: PMC11866248.
2. Ajaikumar B. Kunnumakkara, Preetha Anand, Bharat B. Aggarwal,
Curcumin inhibits proliferation, invasion, angiogenesis and metastasis of different cancers through interaction with multiple cell signaling proteins,
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Front. Pharmacol. 14:1187181. doi: 10.3389/fphar.2023.1187181.
4. Yücel Ç, Karatoprak GŞ, Açıkara ÖB, Akkol EK, Barak TH, Sobarzo-Sánchez E, Aschner M and Shirooie S (2022) Immunomodulatory and anti-inflammatory therapeutic potential of gingerols and their nanoformulations. Front. Pharmacol. 13:902551. doi: 10.3389/fphar.2022.902551
5. Tripathi, A.K., Ray, A.K. & Mishra, S.K. Molecular and pharmacological aspects of piperine as a potential molecule for disease prevention and management: evidence from clinical trials. Beni-Suef Univ J Basic Appl Sci 11, 16 (2022). doi.org/10.1186/s43088-022-00196-1.
6. https://sabinsa.com/sustainability
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8. Curry Powder to Clinical Significance : Curcumin C3 Complex. Muhammed Majeed, Bharat B. Aggarwal, Anurag Pande, and Priti Vaidyanathan. NutriScience Publishers LLC, New Jersey. 2015. ISBN-13:978-0988320918.
9. Curcumin C3 Complex Study Edition 2026. References of all clinical studies, pre-clinical studies, in-vitro studies and review articles involving Curcumin C3 Complex. Published by Sabinsa Corp. 2026. www.sabinsa.com
10. Ayustaningwarno F, Anjani G, Ayu AM, Fogliano V. A critical review of Ginger's (Zingiber officinale) antioxidant, anti-inflammatory, and immunomodulatory activities. Front Nutr. 2024 Jun 6;11:1364836. doi: 10.3389/fnut.2024.1364836. PMID: 38903613; PMCID: PMC11187345.
11. Majeed, Muhammed, and N. Kalyanam, eds. Boswellin®: Anti-Inflammatory Adaptogen from Nature. East Windsor, NJ: NutriScience Publishers LLC, 2020. ISBN-13: 9780988320925
12. Majeed, M., Nagabhushanam, K., Mundkur, L., Thazhathidath, S., Paschapur, M., & Manoharan, T. S. BioPerine®—Nature's Own Supernutrient, Bioavailability Enhancer and Thermonutrient. 2017. NutriScience Publishers LLC, New Jersey. ISBN-13: 9780988320925.
13. https://pubmed.ncbi.nlm.nih.gov/?term=curcumin+C3+complex
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17. Schneider C, Gordon ON, Edwards RL, Luis PB. Degradation of Curcumin: From Mechanism to Biological Implications. J Agric Food Chem. 2015 Sep 9;63(35):7606-14. doi: 10.1021/acs.jafc.5b00244. Epub 2015 Apr 2. PMID: 25817068; PMCID: PMC4752206.
18. Natural Practitioner Magazine. NP 2016 08. https://naturalpractitionermag.com/practitioner-chat-sunil-pai-md-continued/
19. Sunil Pai. An Inflammation Nation: The Definitive 10-Step Guide to Preventing, Reversing and Treating All Diseases with Diet, Lifestyle and the Use of Natural Anti-Inflammatories. RocDoc Publications. 2016. ISBN-13:978-0692514870.
20. Certificates of Analysis and other certificates on file. www.sabinsa.com
21. Boswellin PS Canadian Patent (also patented in Australia, Eurasia, and Taiwan).
22. BOSWELLIN® PS : THE NEXT GENERATION BOSWELLIA SERRATA EXTRACT by Muhammed Majeed, Ph.D., Lakshmi Prakash, Ph.D. Research Report. Sabinsa Corporation. 2009. https://www.becarre-natural.com/products/download-file/289.
23. Sabinsa Corporation and Sami Labs Limited Research data. https://boswellin.com/boswellin-grades/boswellin-ps.
24. Ayustaningwarno F, Anjani G, Ayu AM, Fogliano V. A critical review of Ginger's (Zingiber officinale) antioxidant, anti-inflammatory, and immunomodulatory activities. Front Nutr. 2024 Jun 6;11:1364836. doi: 10.3389/fnut.2024.1364836. PMID: 38903613; PMCID: PMC11187345.
25. Kesarwani K, Gupta R, Mukerjee A. Bioavailability enhancers of herbal origin: an overview. Asian Pac J Trop Biomed. 2013 Apr;3(4):253-66. doi: 10.1016/S2221-1691(13)60060-X. PMID: 23620848; PMCID: PMC3634921.
26. Shoba G, Joy D, Joseph T, Majeed M, Rajendran R, Srinivas PS. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 1998 May;64(4):353-6. doi: 10.1055/s-2006-957450. PMID: 9619120.
27. Bioperine. Sabinsa Corporation. https://bioperine.com/aboutbioperine.
28. Nouri-Vaskeh M, Hashemi P, Hataminia N, Yazdani Y, Nasirian M, Alizadeh L. The impact of piperine on the metabolic conditions of patients with NAFLD and early cirrhosis: a randomized double-blind controlled trial. Sci Rep. 2024 Jan 11;14(1):1053. doi: 10.1038/s41598-024-51726-z. PMID: 38200253; PMCID: PMC10782007.
29. Boretti A. Curcumin-Based Fixed Dose Combination Products for Cholesterol Management: A Narrative Review. ACS Pharmacol Transl Sci. 2024 Jan 9;7(2):300-308. doi: 10.1021/acsptsci.3c00234. PMID: 38357288; PMCID: PMC10863436.
30. Zhou X, Afzal S, Wohlmuth H, Münch G, Leach D, Low M, Li CG. Synergistic Anti-Inflammatory Activity of Ginger and Turmeric Extracts in Inhibiting Lipopolysaccharide and Interferon-γ-Induced Proinflammatory Mediators. Molecules. 2022 Jun 16;27(12):3877. doi: 10.3390/molecules27123877. PMID: 35745000; PMCID: PMC9229778.
31. Sethi V, Garg M, Herve M, Mobasheri A. Potential complementary and/or synergistic effects of curcumin and boswellic acids for management of osteoarthritis. Ther Adv Musculoskelet Dis. 2022 Sep 22;14:1759720X221124545. doi: 10.1177/1759720X221124545. PMID: 36171802; PMCID: PMC9511324.
32. Kunnumakkara AB, Bordoloi D, Padmavathi G, Monisha J, Roy NK, Prasad S, Aggarwal BB. Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases. Br J Pharmacol. 2017 Jun;174(11):1325-1348. doi: 10.1111/bph.13621. Epub 2016 Oct 21. PMID: 27638428; PMCID: PMC5429333.
33. Aggarwal, B. B., & Yost, D. (2011). Healing spices: How to use 50 everyday and exotic spices to boost health and beat disease. Sterling Publishing Company. ISBN-13:978-1402776632.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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